产品编号
KMPH1835
产品名称
Recombinant Human ACE2 Protein, His-tag
产品别称
Angiotensin-converting enzyme 2, ACE2
规格
100ug,1mg
物种
Human
宿主
HEK293 Cells
序列
18-740AA
来源
A DNA sequence encoding the human ACE2 (NP_068576.1) (Gln18-Ser740) was
expressed with a polyhistidine tag at the C-terminus.
纯度
≥95% as determined by SDS-PAGE
内毒素水平
< 1.0 EU per μg of the protein as determined by the LAL method.
缓冲体系
Lyophilized from sterile PBS, pH 7.4.
纯化方式
His Tag Purification
产品背景
Angiotensin-converting enzyme 2 (ACE2) is an enzyme attached to the cell
membranesofcellslocatedinthelungs,arteries,heart,kidney,andintestines.
ACE2lowersbloodpressureby catalyzing thehydrolysisof angiotensinIIinto
angiotensin (1–7). ACE2 counters the activity of therelated
angiotensin-convertingenzyme(ACE)by reducingtheamountofangiotensin-II and
increasing Ang(1-7), making it a promising drug target for treating cardiovascular