华拓生物科技有限公司

中文名称：

 兔抗人、大、小鼠、兔、鸡、猪、犬、牛、羊白细胞介素-10抗体

英文名称：

 Anti-IL-10

产品编号：

 PL030698R

免 疫 原：

 KLH conjugated synthetic peptide derived from human ILvalue="10" hasspace="True" negative="True" numbertype="1" tcsc="0" w:st="on" style="font-family: 'Times New Roman'; font-size: 10.5pt; ">-10 C-terminus

克隆类型：

 Rabbit Polyclonal IgG

产品规格：

 0.1mg/0.2mg

包装情况：

一支包装（原装进口、分装）

其他名称：

 Interleukin-10 precursor; Cytokine synthesis inhibitory factor; CSIF; Cytokine Synthesis Inhibitory Factor; IL 10; ILvalue="10" hasspace="False" negative="False" numbertype="1" tcsc="0" w:st="on" style="font-family: 'Times New Roman'; font-size: 10.5pt; ">10A; Interleukin 10; Interleukin10; MGC126450; MGC126451; TGIF.

背景介绍：

 IL-10 protein is a cytokine produced primarily by monocytes and to a lesser extent by lymphocytes. This cytokine has pleiotropic effects in immunoregulation and inflammation. It down-regulates the expression of Th1 cytokines, MHC class II Ags, and costimulatory molecules on macrophages. It also enhances B cell survival, proliferation, and antibody production. This cytokine can block NF-kappa B activity, and is involved in the regulation of the JAK-STAT signaling pathway. Knockout studies in mice suggested the function of this cytokine as an essential immunoregulator in the intestinal tract. 

交叉反应
       物 种：

Human, Mouse, Rat, Chicken, Pig, Rabbit, Sheep, Guinea Pig,   （Please decide the specificity by homology）