中文名称: |
兔抗人、大、小鼠血管紧张素Ⅱ抗体 |
英文名称: |
Anti-Angiotensin II |
产品编号: |
PL030587R |
免 疫 原: |
(DRVYIHPF-GG)8K4K |
克隆类型: |
Rabbit Polyclonal IgG |
产品规格: |
0.1mg/0.2mg |
产品情况: |
一支包装 |
其他名称: |
Alpha 1 antiproteinase, antitrypsin; Ang II; ANG III; Angiotensin I; Angiotensin II; Angiotensin III; Angiotensinogen; Angiotensinogen (serpin peptidase inhibitor, clade A member 8); ANHU; Pre angiotensinogen; Serine (or cysteine) proteinase inhibitor; Serpin A8; SERPINA8; AT-2; AT-II. |
背景介绍: |
AGT, pre-angiotensinogen or angiotensinogen precursor, is expressed in the liver and is cleaved by the enzyme renin in response to lowered blood pressure. The resulting product, angiotensin I, is then cleaved by angiotensin converting enzyme (ACE) to generate the physiologically active enzyme angiotensin II. The protein is involved in maintaining blood pressure and in the pathogenesis of essential hypertension and preeclampsia. Mutations in this gene are associated with susceptibility to essential hypertension, and can cause renal tubular dysgenesis, a severe disorder of renal tubular development. Defects in this gene have also been associated with non-familial structural atrial fibrillation, and inflammatory bowel disease. |
交叉反应 |
Human, Mouse, Rat, Horse, Sheep, (Please decide the specificity by homology) |
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